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Lorenzo's Oil (1992)
Released By: MCA Universal Home Video   Rating: PG-13   In Theaters: N/A
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Studio: MCA Universal Home Video
Genre: Drama
MPAA Rating: PG-13
Director: George Miller
Language: English
Official Website: N/A
Theatrical Release: N/A
Home Video Release: N/A
Cast: Nick Nolte, Peter Ustinov, Susan Sarandon
Published ID: 3802
UPC: 025192197024,
Plot: Susan Sarandon and Nick Nolte give brilliant performances as parents trying to save the life of their son in George Miller's harrowing and heartbreaking Lorenzo's Oil. Based on a true story, the film begins as bright young Lorenzo (Zack O'Malley Greenburg) is leading a pleasant life on the Comoro Islands. But things start to go wrong with him -- he collapses, he raves, and he loses his hearing -- so his concerned parents, Augusto (Nick Nolte) and Michaela Odone (Susan Sarandon), take him to a doctor. The diagnosis is a death warrant; they are told that Lorenzo has been diagnosed with adrenoleukodystrophy (ALD), an rare and incurable nerve disease that is always fatal. When Augusto and Michaela are told to be patient as they watch their son sink further into the debilitating illness, they take matters into their own hands and start their own investigation of the disease. Using rapeseed oil, they find their own treatment for ALD. ~ Paul Brenner, All Movie Guide
IDDateTimeTitleReviewHelpfulVotesTotalVotes
very moving story
Added 9/6/2009

Lorenzo's oil - more than just a great movie.: An article from: Medical Update is a very moving real life story. It is the emotional journey of the parents of a boy afflicted with a very rare hereditary neurological disorder. Their efforts prolonged their son's life by several years and resulted in the discovery of an oil that can cure the disease if taken early enough in the diagnosis. Susan Sarandon and Nick Nolte offer a wonderful portrayal of these determined parents.
0 out of 0 people found this helpful.
Great educational film
Added 8/17/2009

I have shown this film many times in the high school Biology classes that I teach. The movie does an excellent job following the true story of a family struggling with the genetic disorder ALD. It is sad and painful reminder of the uncertainties associated with genetic disease. My students really enjoy the film and it really puts a face and story behind genetic disease.
0 out of 0 people found this helpful.
The Critics of This Movie Are Ignorant
Added 8/13/2009

Two of the people who gave this movie a bad review (one star) said that the movie was not factual, and even suggested that the oil doesn't work in most ALD patients. I did a web search of only .edu websites and found that the two reviewers are wrong. Lorenzo's oil only works in about 2/3 of ALD patients, that's true. And it only works if those patients start taking the oil *before* the onset of symptoms. But they couldn't be more wrong about the huge breakthrough that Lorenzo's oli represented in the study of ALD. It's just that the cure turns out not to be as simple as was initially hoped.

Do a .edu web search of the following:

Bradley J Stith PhD Lorenzo's oil

He is a professor of biology at Colorado University who thinks that the movie is a great teaching tool for getting students interested in the field of biology. He also discusses every aspect of ALD, the movie, and the oil itself.

Now, as to the charge that doctors and nurses are portrayed negatively in the movie. That's only partially true, because for every doctor and nurse who was portrayed negatively, there were doctors and nurses who were portrayed positively. The doctor who finally diagnosed Lorenzo (in the movie) is played entirely positively, as are all of his nurses and assistants. And the doctor who is in charge of the dietary studies (in the movie) is portrayed only partly negatively; later he even helps the Odones "off the record" in their unprecedented experiment with Lorenzo and the oil. Two of Lorenzo's home care nurses are portrayed partly negatively and partly positively. For that matter, Lorenzo's own mother was portrayed partly negatively because her obsession with Lorenzo was making her start treating her own family members badly in some ways. Of course, she can be excused because she was a panic-stricken and desperate mother.

Don't listen to the naysayers. All of their claims are off-target. This movie is on my list of top ten films ever made.

1 out of 1 people found this helpful.
Depressing, yet hauntingly beautiful
Added 3/22/2009

Back in my High School years, I had to watch "Lorenzo's Oil" in Biology class. I thought I would be bored straight through, but it caught my attention. Now I can see why it's so good. It's a hauntingly beautiful film that would most certainly cause tidal waves of tears for those who are easily saddened. Nolte and Sarandon are fantastic as the couple that would never give up on their own damaged son (although Nolte's accent can be a bit laughable). Samuel Barber's "Adagio for Strings" is a nice touch as well. I would only recommend this film to those who are interested in science and good drama, but not to those who would NEVER want to see a kid's life being torn apart by a rare disease. Keep in mind that it's based on a true story; that's what makes this film more mesmerizing than it is.

R.I.P. Lorenzo Odone

0 out of 0 people found this helpful.
Bookbug
Added 1/31/2009

This story about parents researching a treatment for their son's incurable and untreatable ALD disease in spite of a general lack of real support is inspiring. They persevered when their support group leaders insisted they needed to accept their son's death. When doctors were horrified that anyone without a medical degree would experiment on their own son to find a cure - even though the result of NOT trying and evaluating possible medications was disability, dementia, and death, they didn't give up. This medical drama is well produced. It will keep you on the edge of your seat and cheering to the end. Although the story isn't finished yet, the "end" is satisfying and challenging.
0 out of 0 people found this helpful.
very moving story
Added 9/6/2009

Lorenzo's oil - more than just a great movie.: An article from: Medical Update is a very moving real life story. It is the emotional journey of the parents of a boy afflicted with a very rare hereditary neurological disorder. Their efforts prolonged their son's life by several years and resulted in the discovery of an oil that can cure the disease if taken early enough in the diagnosis. Susan Sarandon and Nick Nolte offer a wonderful portrayal of these determined parents.
0 out of 0 people found this helpful.
Great educational film
Added 8/17/2009

I have shown this film many times in the high school Biology classes that I teach. The movie does an excellent job following the true story of a family struggling with the genetic disorder ALD. It is sad and painful reminder of the uncertainties associated with genetic disease. My students really enjoy the film and it really puts a face and story behind genetic disease.
0 out of 0 people found this helpful.
The Critics of This Movie Are Ignorant
Added 8/13/2009

Two of the people who gave this movie a bad review (one star) said that the movie was not factual, and even suggested that the oil doesn't work in most ALD patients. I did a web search of only .edu websites and found that the two reviewers are wrong. Lorenzo's oil only works in about 2/3 of ALD patients, that's true. And it only works if those patients start taking the oil *before* the onset of symptoms. But they couldn't be more wrong about the huge breakthrough that Lorenzo's oli represented in the study of ALD. It's just that the cure turns out not to be as simple as was initially hoped.

Do a .edu web search of the following:

Bradley J Stith PhD Lorenzo's oil

He is a professor of biology at Colorado University who thinks that the movie is a great teaching tool for getting students interested in the field of biology. He also discusses every aspect of ALD, the movie, and the oil itself.

Now, as to the charge that doctors and nurses are portrayed negatively in the movie. That's only partially true, because for every doctor and nurse who was portrayed negatively, there were doctors and nurses who were portrayed positively. The doctor who finally diagnosed Lorenzo (in the movie) is played entirely positively, as are all of his nurses and assistants. And the doctor who is in charge of the dietary studies (in the movie) is portrayed only partly negatively; later he even helps the Odones "off the record" in their unprecedented experiment with Lorenzo and the oil. Two of Lorenzo's home care nurses are portrayed partly negatively and partly positively. For that matter, Lorenzo's own mother was portrayed partly negatively because her obsession with Lorenzo was making her start treating her own family members badly in some ways. Of course, she can be excused because she was a panic-stricken and desperate mother.

Don't listen to the naysayers. All of their claims are off-target. This movie is on my list of top ten films ever made.

1 out of 1 people found this helpful.
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